@import url(https://fonts.googleapis.com/css2?family=Inter:wght@400;600&display=swap);@import url(https://fonts.googleapis.com/css2?family=Merriweather:wght@300&display=swap);@import url(https://fonts.googleapis.com/css2?family=Nunito:wght@200&display=swap);@import url(https://fonts.googleapis.com/css2?family=Poppins:wght@100&display=swap);@import url(https://fonts.googleapis.com/css2?family=IBM+Plex+Sans:wght@200&display=swap);@import url(https://fonts.googleapis.com/css2?family=Lato:wght@300&display=swap);.login-page{align-items:center;background:#000;box-sizing:border-box;display:flex;flex-direction:column;gap:24px;height:100vh;justify-content:flex-start;overflow-y:auto;padding:24px;scrollbar-color:#fff6 #ffffff05;scrollbar-width:thin}.login-page::-webkit-scrollbar{width:8px}.login-page::-webkit-scrollbar-track{background:#ffffff05}.login-page::-webkit-scrollbar-thumb{background:#fff6;border-radius:8px}.login-page::-webkit-scrollbar-thumb:hover{background:#fffc}.login-page>:not(.video-frame){position:relative;z-index:10}.login-page>*{flex-shrink:0}.video-frame{position:relative;width:min(640px,90vw);z-index:1}.login-header{align-items:center;display:flex;justify-content:center;margin-top:-20px;width:min(640px,90vw)}p.welcome-text{color:#dadada;line-height:1.65;margin-bottom:-20px;margin-top:-10px;text-align:center}.welcome-text-description{background:#ffffff0d;border:1px solid #ffffff1a;border-radius:10px;box-shadow:inset 0 2px 10px #0000004d;box-sizing:border-box;color:#dadada;flex-shrink:1;font-size:14px;line-height:1.65;margin-bottom:16px;margin-top:8px;min-height:200px;overflow-y:auto;padding:16px 24px;scrollbar-color:#fff6 #ffffff05;scrollbar-width:thin;text-align:left;width:min(580px,90vw)}.welcome-text-description::-webkit-scrollbar{width:8px}.welcome-text-description::-webkit-scrollbar-track{background:#ffffff05;border-radius:8px}.welcome-text-description::-webkit-scrollbar-thumb{background:#fff6;border-radius:8px}.welcome-text-description::-webkit-scrollbar-thumb:hover{background:#fff9}.welcome-text-description p{margin-bottom:12px;margin-top:0}.welcome-text-description p:last-child{margin-bottom:0}.welcome-text-description a{color:#7dd3fc;text-decoration:none}.welcome-text-description a:hover{text-decoration:underline}.login-title{color:#fff;font-family:IBM Plex Sans,sans-serif;font-size:28px;font-weight:700;letter-spacing:.3px;margin-top:-40px}.login-canvas,.login-video{aspect-ratio:16/9;background:#0b0b0b;border-radius:16px;box-shadow:0 8px 24px #00000040,inset 0 1px 0 #fff3;display:block;height:auto;margin-bottom:-50px;margin-left:32px;margin-top:-50px;width:100%}.login-button{-webkit-appearance:none;appearance:none;background:linear-gradient(135deg,#2563eb,#0ea5e9 50%,#14b8a6);border:0;border-radius:9999px;box-shadow:0 6px 20px #00000040;color:#fff;cursor:pointer;font-size:1.15rem;font-weight:600;line-height:1.61;padding:20px 30px;transition:transform .06s ease,box-shadow .2s ease,filter .2s ease}.login-button:hover{box-shadow:0 10px 28px #0000004d;filter:brightness(1.05);transform:translateY(-1px)}.login-button:active{box-shadow:0 4px 12px #00000047;filter:brightness(.98);transform:translateY(0)}.login-button:focus-visible{box-shadow:0 0 0 3px #0ea5e98c,0 6px 20px #00000040;outline:none}.login-alt{color:#cbd5f5;font-size:.98rem;margin:0;text-align:center}.login-link{color:#7dd3fc;font-weight:600;text-decoration:none}.login-link:hover{text-decoration:underline}body.login-body{background:#000;margin:0;overflow:hidden}body.dark-mode{background-color:#222;color:#ddd}body.light-mode{background-color:#fff}.combobox,header,input[type=text]{transition:background-color .3s,color .3s}body.dark-mode #myGrid .ag-root-wrapper{background-color:#222}body.light-mode #myGrid .ag-root-wrapper{background-color:#fff}body.light-mode{--modal-bg:#fff;--modal-fg:#111;--modal-border:#ccc;background:#fff;color:#000;font-family:Inter,sans-serif}body.dark-mode{--modal-bg:#2a2a2a;--modal-fg:#eee;--modal-border:#555;background:#1e1e1e;color:#ccc;font-family:Inter,sans-serif}a{cursor:pointer;text-decoration:none}.light-mode a,.light-mode a:visited{color:#000}.dark-mode a{color:#fff}.light-mode a:active,.light-mode a:focus,.light-mode a:hover{color:#000}.dark-mode a:active,.dark-mode a:focus,.dark-mode a:hover{color:#fff}#search-bar{padding-right:40px;text-align:center}#disease-filter{font-family:Inter,sans-serif;font-size:13px;max-width:500px;min-width:500px;padding-left:25px;padding-right:0;padding-top:11px;position:relative;z-index:9999!important}#disease-filter>input{width:60%}#disease-filter div{border-radius:18px;padding-left:4px}#disease-filter .select__menu{min-width:250px;width:100%!important;z-index:99999!important}#disease-filter .select__option label{color:#000!important}#disease-filter .select__control,#disease-filter .select__input-container,#disease-filter .select__multi-value__label,#disease-filter .select__single-value{color:#333}body.dark-mode #disease-filter .select__control,body.dark-mode #disease-filter .select__input-container,body.dark-mode #disease-filter .select__multi-value__label,body.dark-mode #disease-filter .select__single-value{color:#ddd}#reset-anchor{cursor:pointer;padding-left:0}#reset-anchor .icon{cursor:pointer;font-size:32px;margin-top:10px;padding-left:1px}#medgen-filter-icon .icon{font-size:32px;margin-right:-21px;margin-top:10px;padding-right:0;vertical-align:bottom}#quickFilter{border:2px solid #ccc;border-radius:20px;box-shadow:0 2px 4px #0000001a;font-size:16px;padding:10px 15px;vertical-align:top;width:60%}.protein-list-link-icon{font-size:14px;margin-bottom:3px;vertical-align:middle}.protein-link-icon{margin-bottom:2.5px}.material-symbols-outlined.protein-link-icon,.material-symbols-outlined.protein-list-link-icon,.protein-link-icon{font-size:14px;vertical-align:middle}.icon{font-size:48px;vertical-align:bottom}#div-logo{display:block;margin:0 auto;padding-left:27px;text-align:center}#div-logo>img{display:block;height:auto;margin:10px auto 0;width:20%}h2,h3{font-family:Inter,sans-serif;margin:20px;text-align:center}#h2-main{font-size:75px;font-weight:100;margin-top:0}#h2-main,#h3-main{font-family:IBM Plex Sans,sans-serif}#h3-main{font-family:Lato,sans-serif;font-size:30px;font-weight:400;letter-spacing:10000;margin-top:-18px;padding-bottom:5px}.theme-toggle-container{font-family:Inter,sans-serif;margin:20px;position:absolute}.theme-toggle-container a{cursor:pointer}#tissue-specificity-note{font-size:16px}#tissue-specificity-link{font-size:15px;margin-top:0}#tissue-specificity-note li{font-size:inherit}#tissue-specificity-note p{margin-bottom:5px}#tissue-specificity-note ul{margin-top:0}#protein-info-table .icon,#tissue-specificity-note .icon{font-size:15px;margin-bottom:4px;margin-left:3px}#protein-info-table{border-collapse:collapse;table-layout:fixed;width:100%}#protein-info-table td,#protein-info-table th{box-sizing:border-box;padding:8px;text-align:left;vertical-align:top;width:50%}.table-container{font-family:Inter,sans-serif;margin:20px}a.target-full-name{color:#fff;cursor:pointer}.dataTables_wrapper .dataTables_filter input{font-family:Inter,sans-serif;margin-left:.5em;width:300px}body.dark-mode table.dataTable tbody tr{font-family:Inter,sans-serif}#myGrid{padding-top:12px}.custom-toggle-group{border:1px solid #ccc;border-radius:20px;box-shadow:0 2px 5px #0000001a;display:inline-flex;margin-bottom:18px;margin-top:3px;overflow:hidden}.custom-toggle-button{background-color:#fff;border:none;color:#333;cursor:pointer;font-size:14px;line-height:1;padding:12px 20px;transition:background-color .2s ease-in-out,color .2s ease-in-out}.user-email{opacity:.8;padding-left:2px;padding-right:2px}.custom-toggle-button:not(:last-child){border-right:1px solid #ccc}.custom-toggle-button.active{background-color:#5a5a5a;color:#fff}.custom-toggle-button:hover:not(.active){background-color:#e0e0e0}.custom-toggle-button:disabled{border-color:#ddd;cursor:not-allowed}.custom-toggle-button:disabled,.custom-toggle-button:disabled:hover{background-color:#f0f0f0;color:#aaa}body.dark-mode .custom-toggle-group{border-color:#555}body.dark-mode .custom-toggle-button{background-color:#444;color:#ccc}body.dark-mode .custom-toggle-button:not(:last-child){border-right:1px solid #555}body.dark-mode .custom-toggle-button.active{background-color:#777;color:#fff}body.dark-mode .custom-toggle-button:hover:not(.active){background-color:#666}body.dark-mode .custom-toggle-button:disabled{background-color:#3a3a3a;border-color:#4a4a4a;color:#777}body.dark-mode .custom-toggle-button:disabled:hover{background-color:#3a3a3a;color:#777}.powered-by-ibm-logo-container{bottom:10px;position:fixed;right:10px;z-index:10000}.powered-by-ibm-logo-container img{height:25px;width:auto}.icon-btn{align-items:center;-webkit-appearance:none;appearance:none;background:#0000000a;border:1px solid #c7c7c7;border-radius:999px;color:inherit;cursor:pointer;display:inline-flex;height:34px;justify-content:center;transition:background .2s,border-color .2s,box-shadow .2s,color .2s,transform .02s;width:34px}.icon-btn:hover{background:#00000014}.icon-btn:active{transform:translateY(1px)}.icon-btn:focus-visible{outline:2px solid #4c9ffe;outline-offset:2px}.theme-icon{font-size:20px;line-height:1}.pill-btn{-webkit-appearance:none;appearance:none;background:#fff;border:1px solid #c7c7c7;border-radius:999px;color:#333;cursor:pointer;font-size:14px;line-height:1.2;padding:6px 12px;transition:background .2s,border-color .2s,color .2s,box-shadow .2s}.pill-btn:hover{background:#f3f3f3}.pill-btn:focus-visible{outline:2px solid #4c9ffe;outline-offset:2px}.studies-pill-btn{line-height:1;padding:12px 20px}.studies-pill-btn:disabled,.studies-pill-btn:disabled:hover{background:#fff;color:#aaa;cursor:not-allowed}body.dark-mode .studies-pill-btn:disabled,body.dark-mode .studies-pill-btn:disabled:hover{background:#2a2a2a;color:#777}.pill-btn-primary{background:#0d6efd;border-color:#0b5ed7;color:#fff}.pill-btn-primary:hover{background:#0b5ed7}.pill-btn-danger{border-color:#b00020;color:#b00020}.pill-btn-danger:hover{background:#b00020;color:#fff}body.dark-mode .icon-btn{background:#2a2a2a;border-color:#555;color:#e0e0e0}body.dark-mode .icon-btn:hover{background:#333}body.dark-mode .pill-btn{background:#2a2a2a;border-color:#555;color:#e0e0e0}body.dark-mode .pill-btn:hover{background:#333}body.dark-mode .pill-btn-primary{background:#1a5bdb;border-color:#2573ff;color:#fff}body.dark-mode .pill-btn-primary:hover{background:#174fc0}.filter-cat-group{align-items:center;display:flex;flex-wrap:wrap;gap:12px;justify-content:center;margin:10px 0 8px}.filter-cat-btn{-webkit-appearance:none;appearance:none;background:#fff;border:1px solid #c7c7c7;border-radius:999px;color:#333;cursor:pointer;font-size:15px;line-height:1.2;padding:10px 22px;transition:background .15s,border-color .15s,color .15s,box-shadow .15s}.filter-cat-btn:hover{background:#f3f3f3}.filter-cat-btn:focus-visible{outline:2px solid #4c9ffe;outline-offset:2px}.filter-cat-btn.active{background:#1f5aa8;border-color:#163e7a;box-shadow:0 1px 4px #1f5aa866;color:#fff}.filter-cat-btn.active:hover{background:#163e7a;border-color:#102d59}body.dark-mode .filter-cat-btn{background:#2a2a2a;border-color:#555;color:#e0e0e0}body.dark-mode .filter-cat-btn:hover{background:#333}body.dark-mode .filter-cat-btn.active{background:#2a6fc7;border-color:#1f5aa8;box-shadow:0 1px 4px #2a6fc780;color:#fff}body.dark-mode .filter-cat-btn.active:hover{background:#1f5aa8;border-color:#163e7a}.filter-cat-deselect-hint{font-size:.78rem;margin:0 0 8px;opacity:.6;text-align:center}.user-controls-container .material-symbols-outlined{line-height:1;vertical-align:middle}body.light-mode #detectionsGrid{--ag-foreground-color:#000;--ag-data-color:#000;--ag-cell-text-color:#000;--ag-header-text-color:#000;--ag-secondary-foreground-color:#000}body.light-mode #detectionsGrid .ag-cell-value,body.light-mode #detectionsGrid .ag-header-cell-text,body.light-mode #detectionsGrid .ag-root-wrapper,body.light-mode #detectionsGrid .detail-wrapper{--ag-text-color:#000;color:#000!important}body.light-mode #detectionsGrid,body.light-mode #detectionsGrid .ag-cell,body.light-mode #detectionsGrid .ag-cell-value,body.light-mode #detectionsGrid .ag-header-cell-text,body.light-mode #detectionsGrid .detail-wrapper,body.light-mode #detectionsGrid .detail-wrapper *,body.light-mode #detectionsGrid a,body.light-mode #detectionsGrid a:hover{color:#000!important}.mesh-tree-filter{border:1px solid #00000021;border-radius:10px;font-size:13.5px;margin:0 auto 12px;overflow:hidden;width:85%}body.dark-mode .mesh-tree-filter{border-color:#ffffff1f}.mesh-tree-toolbar{align-items:center;background:#00000008;border-bottom:1px solid #0000001a;display:flex;gap:8px;padding:8px 12px}body.dark-mode .mesh-tree-toolbar{background:#ffffff0a;border-bottom-color:#ffffff14}.mesh-tree-search{background:#0000;border:1px solid #ccc;border-radius:999px;color:inherit;flex:1 1;font-size:13px;min-width:0;outline:none;padding:5px 12px}body.dark-mode .mesh-tree-search{border-color:#555}.mesh-tree-search:focus{border-color:#4c9ffe;box-shadow:0 0 0 2px #4c9ffe33}.mesh-tree-selection-label{font-size:12px;opacity:.75;white-space:nowrap}.mesh-tree-reset{align-items:center;-webkit-appearance:none;appearance:none;background:#0000;border:none;border-radius:6px;color:inherit;cursor:pointer;display:flex;opacity:.7;padding:2px;transition:opacity .15s}.mesh-tree-reset:hover{opacity:1}.mesh-tree-reset:disabled{cursor:default;opacity:.25}.mesh-tree-col-header{align-items:center;border-bottom:1px solid #8080802e;display:flex;font-size:11px;font-weight:600;letter-spacing:.04em;margin:0 4px 2px;opacity:.55;padding:6.5px 12px 4px 22px;text-transform:uppercase;-webkit-user-select:none;user-select:none}.mesh-tree-col-header-label{flex:1 1;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.mesh-tree-col-header-count{flex-shrink:0;min-width:22px;padding:0 6px;text-align:center}.mesh-tree-scroll{max-height:260px;overflow-y:auto;padding:4px 0;scrollbar-color:#80808066 #0000;scrollbar-width:thin}.mesh-tree-scroll::-webkit-scrollbar{width:6px}.mesh-tree-scroll::-webkit-scrollbar-track{background:#0000}.mesh-tree-scroll::-webkit-scrollbar-thumb{background:#80808066;border-radius:6px}.mesh-tree-node{align-items:center;border-radius:5px;cursor:pointer;display:flex;gap:4px;margin:1px 4px;padding:3px 12px 3px 4px;transition:background .1s;-webkit-user-select:none;user-select:none}.mesh-tree-node:hover{background:#4c9ffe1a}.mesh-tree-node--selected{background:#4c9ffe2e!important;font-weight:600}body.dark-mode .mesh-tree-node:hover{background:#ffffff12}body.dark-mode .mesh-tree-node--selected{background:#ffffff1f!important}.mesh-tree-toggle{display:inline-block;flex-shrink:0;font-size:11px;opacity:.6;text-align:center;width:14px}.mesh-tree-label{flex:1 1;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.mesh-tree-count{background:#80808026;border-radius:999px;flex-shrink:0;font-size:11px;min-width:22px;opacity:.55;padding:1px 6px;text-align:center}.filter-mode-toggle{align-items:center;display:flex;gap:0;justify-content:center;margin:12px auto}.filter-mode-btn{-webkit-appearance:none;appearance:none;background:#fff;border:1px solid #ccc;color:#333;cursor:pointer;font-size:13px;line-height:1.3;padding:6px 16px;transition:background .15s,color .15s}.filter-mode-btn:first-child{border-radius:999px 0 0 999px}.filter-mode-btn:not(:last-child){border-right:none}.filter-mode-btn:last-child{border-radius:0 999px 999px 0}.filter-mode-btn.active{background:#5a5a5a;border-color:#5a5a5a;color:#fff}.filter-mode-btn:hover:not(.active){background:#f0f0f0}body.dark-mode .filter-mode-btn{background:#2a2a2a;border-color:#555;color:#ddd}body.dark-mode .filter-mode-btn.active{background:#666;border-color:#666;color:#fff}body.dark-mode .filter-mode-btn:hover:not(.active){background:#383838}.mesh-d3-container{border:1px solid #00000021;border-radius:10px;margin:0 auto 12px;overflow:hidden;width:85%}body.dark-mode .mesh-d3-container{border-color:#ffffff1f}.mesh-d3-infobar{align-items:center;background:#00000005;border-bottom:1px solid #00000017;display:flex;font-size:13px;gap:8px;min-height:34px;padding:7px 12px}body.dark-mode .mesh-d3-infobar{background:#ffffff08;border-bottom-color:#ffffff12}.mesh-d3-hover-name{font-weight:600}.mesh-d3-hover-name,.mesh-d3-selected-name{flex:1 1;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.mesh-d3-selected-name{color:#4c9ffe}body.dark-mode .mesh-d3-selected-name{color:#6db8ff}.mesh-d3-hint{flex:1 1;font-size:.84rem;opacity:.5}.mesh-view-toggle{margin-bottom:8px;margin-top:-4px}.mesh-view-btn{margin-bottom:12px;margin-top:12px;padding:12px}.site-nav{align-items:center;border-bottom:1px solid #80808033;display:flex;font-family:Inter,sans-serif;gap:0;height:54px;padding:0 20px;position:-webkit-sticky;position:sticky;top:0;z-index:1000}.site-nav-light{background:#fff;border-bottom-color:#e0e0e0;color:#212529}.site-nav-dark{background:#1a1a1a;border-bottom-color:#333;color:#e0e0e0}.site-nav-brand{flex-shrink:0;margin-right:28px}.site-nav-brand a{align-items:center;color:inherit;display:flex;gap:10px;text-decoration:none}.site-nav-logo{display:block;height:28px;width:auto}.site-nav-title{font-family:IBM Plex Sans,sans-serif;font-size:15px;font-weight:600;letter-spacing:.01em;white-space:nowrap}.site-nav-links{align-items:center;display:flex;flex:1 1;gap:4px;list-style:none;margin:0;padding:0}.site-nav-link{align-items:center;border-radius:6px;color:inherit;display:inline-flex;font-size:14px;font-weight:500;gap:5px;opacity:.75;padding:6px 12px;text-decoration:none;transition:background .15s,color .15s}.site-nav-link:focus-visible,.site-nav-link:hover{opacity:1}.site-nav-link-active{font-weight:600;opacity:1}.site-nav-icon{font-size:17px;line-height:1}.site-nav-light .site-nav-link:focus-visible,.site-nav-light .site-nav-link:hover{background:#0000000f;color:#000}.site-nav-light .site-nav-link-active{background:#0d6efd1a;color:#0d6efd}.site-nav-dark .site-nav-link:focus-visible,.site-nav-dark .site-nav-link:hover{background:#ffffff14;color:#fff}.site-nav-dark .site-nav-link-active{background:#63a0ff26;color:#7dbbff}.site-nav-controls{align-items:center;display:flex;flex-shrink:0;gap:8px}.site-nav-username{font-size:14px;font-weight:600}.site-nav-useremail{font-size:13px;opacity:.7}.content-page{padding:40px 20px 60px}.content-page-inner{font-family:Inter,sans-serif;line-height:1.7;margin:0 auto;max-width:780px}.content-page-title{border-bottom:2px solid #80808033;font-family:IBM Plex Sans,sans-serif;font-size:2rem;font-weight:300;margin-bottom:36px;padding-bottom:16px}.content-section{margin-bottom:36px}.content-section h2{font-size:1.15rem;font-weight:600;margin:0 0 10px;text-align:left}.content-section h3{font-size:1rem;font-weight:600;margin:18px 0 6px;text-align:left}.content-section p{margin:0 0 12px}.content-section ul{margin:0 0 12px 1.2em;padding:0}.content-section li{margin-bottom:6px}body.light-mode .content-page-title{border-bottom-color:#ddd;color:#111}body.dark-mode .content-page-title{border-bottom-color:#333;color:#e8e8e8}body.light-mode .content-section a{color:#0d6efd}body.dark-mode .content-section a{color:#7dbbff}body,body *,html,html *{scrollbar-width:thin}body.dark-mode,body.dark-mode *,html:has(body.dark-mode){scrollbar-color:#fff6 #0000!important}body.light-mode,body.light-mode *,html:has(body.light-mode){scrollbar-color:#00000059 #0000!important}body ::-webkit-scrollbar,body ::-webkit-scrollbar-corner,body ::-webkit-scrollbar-track,body ::-webkit-scrollbar-track-piece,body::-webkit-scrollbar,body::-webkit-scrollbar-corner,body::-webkit-scrollbar-track,body::-webkit-scrollbar-track-piece,html ::-webkit-scrollbar,html ::-webkit-scrollbar-corner,html ::-webkit-scrollbar-track,html ::-webkit-scrollbar-track-piece,html::-webkit-scrollbar,html::-webkit-scrollbar-corner,html::-webkit-scrollbar-track,html::-webkit-scrollbar-track-piece{background:#0000!important;background-color:initial!important;border:0!important;box-shadow:none!important;outline:0!important}body ::-webkit-scrollbar,body::-webkit-scrollbar,html ::-webkit-scrollbar,html::-webkit-scrollbar{height:8px!important;width:8px!important}body ::-webkit-scrollbar-button,body::-webkit-scrollbar-button,html ::-webkit-scrollbar-button,html::-webkit-scrollbar-button{background:#0000!important;display:none!important;height:0!important;width:0!important}body.dark-mode ::-webkit-scrollbar-thumb,body.dark-mode::-webkit-scrollbar-thumb{background:#fff6!important;border:0!important;border-radius:8px!important;box-shadow:none!important}body.dark-mode ::-webkit-scrollbar-thumb:hover,body.dark-mode::-webkit-scrollbar-thumb:hover{background:#fff9!important}body.light-mode ::-webkit-scrollbar-thumb,body.light-mode::-webkit-scrollbar-thumb{background:#00000059!important;border:0!important;border-radius:8px!important;box-shadow:none!important}body.light-mode ::-webkit-scrollbar-thumb:hover,body.light-mode::-webkit-scrollbar-thumb:hover{background:#0000008c!important}.whatsnew-banner{align-items:center;border:1px solid var(--modal-border);border-radius:8px;display:flex;font-size:.9rem;gap:10px;margin:0 auto 14px;max-width:900px;padding:8px 12px}body.light-mode .whatsnew-banner{background:#f4f8ff}body.dark-mode .whatsnew-banner{background:#26303c}.whatsnew-banner-icon{font-size:20px;opacity:.75}.whatsnew-banner-text{flex:1 1 auto}.whatsnew-banner-link{background:none;border:none;color:#0d6efd;cursor:pointer;flex:0 0 auto;font:inherit;padding:0 4px;text-decoration:underline}body.dark-mode .whatsnew-banner-link{color:#7fb2ff}.whatsnew-banner-close{align-items:center;background:none;border:none;color:inherit;cursor:pointer;display:inline-flex;flex:0 0 auto;opacity:.45;padding:2px;transition:opacity .15s ease}.whatsnew-banner-close:focus-visible,.whatsnew-banner-close:hover,.whatsnew-banner:hover .whatsnew-banner-close{opacity:1}.whatsnew-banner-close .material-symbols-outlined{font-size:18px}.whatsnew-overlay{align-items:center;background:#00000073;display:flex;inset:0;justify-content:center;padding:20px;position:fixed;z-index:1000}.whatsnew-modal{background:var(--modal-bg);border:1px solid var(--modal-border);border-radius:10px;box-shadow:0 12px 32px #00000059;color:var(--modal-fg);max-height:80vh;overflow-y:auto;padding:20px 22px;width:min(620px,100%)}.whatsnew-modal-title{font-size:1.15rem;margin:0 0 14px}.whatsnew-modal-actions{display:flex;gap:8px;justify-content:flex-end;margin-top:16px}.whatsnew-list{list-style:none;margin:0;padding:0}.whatsnew-entry{padding:10px 0}.whatsnew-entry+.whatsnew-entry{border-top:1px solid var(--modal-border)}.whatsnew-entry-head{align-items:baseline;display:flex;flex-wrap:wrap;gap:8px}.whatsnew-entry-title{font-weight:600}.whatsnew-entry-date{font-size:.82rem;opacity:.7;white-space:nowrap}.whatsnew-kind{border:1px solid;border-radius:999px;flex:0 0 auto;font-size:.7rem;letter-spacing:.04em;opacity:.85;padding:2px 7px;text-transform:uppercase}.whatsnew-kind-feature{color:#0d6efd}.whatsnew-kind-data{color:#1a8754}.whatsnew-kind-fix{color:#b8860b}.whatsnew-kind-maintenance{color:#6c757d}body.dark-mode .whatsnew-kind-feature{color:#7fb2ff}body.dark-mode .whatsnew-kind-data{color:#5cd6a0}body.dark-mode .whatsnew-kind-fix{color:#e0b755}body.dark-mode .whatsnew-kind-maintenance{color:#a5adb5}.whatsnew-count{background:none;border:1px solid var(--modal-border);border-radius:999px;color:inherit;cursor:pointer;font:inherit;font-size:.75rem;opacity:.8;padding:1px 7px}.whatsnew-count:hover{opacity:1}.whatsnew-dates{flex-basis:100%;font-size:.82rem;margin:6px 0 0;opacity:.75;padding-left:18px}.whatsnew-entry-detail{margin:6px 0 0}.whatsnew-entry-items{margin:6px 0 0;padding-left:20px}.whatsnew-proteins{display:flex;flex-wrap:wrap;font-size:.85rem;gap:4px 10px;list-style:none;margin:8px 0 0;padding:0}.whatsnew-proteins a{text-decoration:underline}.whatsnew-proteins-more{opacity:.7}.whatsnew-empty{opacity:.75}.news-admin{padding:16px}.news-admin-head{align-items:center;display:flex;gap:12px;justify-content:space-between;margin-bottom:12px}.news-admin-intro{margin:0 0 16px;max-width:70ch;opacity:.85}.news-admin-error{border:1px solid #b00020;border-radius:6px;color:#b00020;margin-bottom:12px;padding:8px 12px}.news-admin-cols{grid-gap:28px;align-items:start;display:grid;gap:28px;grid-template-columns:minmax(280px,380px) 1fr}@media (max-width:900px){.news-admin-cols{grid-template-columns:1fr}}.news-admin-form{grid-gap:12px;border:1px solid var(--modal-border);border-radius:8px;display:grid;gap:12px;padding:16px}.news-admin-form h3,.news-admin-listcol h3{margin:0 0 4px}.news-admin-form label{grid-gap:4px;display:grid;font-size:.88rem;gap:4px}.news-admin-form input[type=date],.news-admin-form input[type=text],.news-admin-form select,.news-admin-form textarea{background:#0000;border:1px solid var(--modal-border);border-radius:6px;color:inherit;font:inherit;padding:6px 8px;width:100%}.news-admin-form textarea{resize:vertical}.news-admin-check{align-items:center;display:flex!important;gap:8px}.news-admin-hint{font-size:.78rem;opacity:.7}.news-admin-actions{display:flex;gap:8px;justify-content:flex-end}.news-admin-table{border-collapse:collapse;font-size:.88rem;width:100%}.news-admin-table td,.news-admin-table th{border-bottom:1px solid var(--modal-border);padding:6px 10px 6px 0;text-align:left;vertical-align:top}.news-admin-table tr.is-editing{outline:2px solid #0d6efd}.news-admin-nowrap{white-space:nowrap}.news-admin-muted{opacity:.6}.news-admin-major{border:1px solid;border-radius:999px;color:#b8860b;font-size:.7rem;margin-left:8px;padding:1px 6px;text-transform:uppercase}body.dark-mode .news-admin-major{color:#e0b755}.news-admin-status{background:none;border:1px solid var(--modal-border);border-radius:999px;color:inherit;cursor:pointer;font:inherit;font-size:.78rem;opacity:.7;padding:2px 10px}.news-admin-status.is-published{border-color:#1a8754;color:#1a8754;opacity:1}body.dark-mode .news-admin-status.is-published{border-color:#5cd6a0;color:#5cd6a0}.news-admin-preview{font-size:.88rem;list-style:none;margin:0;padding:0}.news-admin-preview li{border-bottom:1px solid var(--modal-border);padding:4px 0}.news-admin-count{border:1px solid var(--modal-border);border-radius:999px;font-size:.75rem;margin-left:8px;padding:0 6px}.disease-group-filter{margin:0 auto 14px;width:85%}.disease-group-buttons{display:flex;flex-wrap:wrap;gap:8px;justify-content:center}.disease-group-btn{align-items:center;-webkit-appearance:none;appearance:none;background:#fff;border:1px solid #ccc;border-radius:999px;color:#333;cursor:pointer;display:inline-flex;font-size:13px;gap:7px;line-height:1.3;padding:6px 14px 6px 10px;transition:background .15s,color .15s,border-color .15s}.disease-group-btn:hover:not(.active){background:#f0f0f0}.disease-group-btn:focus-visible{outline:2px solid #4c9ffe;outline-offset:2px}.disease-group-dot{background:#0000;border:1px solid #999;border-radius:50%;flex:none;height:12px;width:12px}.disease-group-btn.active{background:#5a5a5a;border-color:#5a5a5a;color:#fff}.disease-group-btn.active .disease-group-dot{background:#fff;border-color:#fff;box-shadow:inset 0 0 0 2px #5a5a5a}.disease-group-count{font-feature-settings:"tnum";font-size:11px;font-variant-numeric:tabular-nums;opacity:.65}.disease-group-controls{align-items:center;display:flex;flex-wrap:wrap;gap:14px;justify-content:center;margin-top:12px}.disease-group-switch{align-items:center;cursor:pointer;display:inline-flex;gap:9px;-webkit-user-select:none;user-select:none}.disease-group-switch.idle{opacity:.6}.disease-group-switch input{height:0;opacity:0;position:absolute;width:0}.disease-group-switch-track{background:#ccc;border-radius:999px;flex:none;height:20px;position:relative;transition:background .15s;width:38px}.disease-group-switch-knob{background:#fff;border-radius:50%;height:16px;left:2px;position:absolute;top:2px;transition:transform .15s;width:16px}.disease-group-switch input:checked+.disease-group-switch-track{background:#4c9ffe}.disease-group-switch input:checked+.disease-group-switch-track .disease-group-switch-knob{transform:translateX(18px)}.disease-group-switch input:focus-visible+.disease-group-switch-track{outline:2px solid #4c9ffe;outline-offset:2px}.disease-group-switch-text{display:flex;flex-direction:column;font-size:12.5px;line-height:1.35}.disease-group-switch-hint{font-size:11.5px;opacity:.65}.disease-group-empty{font-size:13px;opacity:.7;text-align:center}body.dark-mode .disease-group-btn{background:#2a2a2a;border-color:#555;color:#ddd}body.dark-mode .disease-group-btn:hover:not(.active){background:#383838}body.dark-mode .disease-group-btn.active{background:#666;border-color:#666;color:#fff}body.dark-mode .disease-group-btn.active .disease-group-dot{box-shadow:inset 0 0 0 2px #666}body.dark-mode .disease-group-dot{border-color:#888}body.dark-mode .disease-group-switch-track{background:#555}.disease-group-links{align-items:center;display:flex;flex-direction:column;gap:2px;margin-top:10px}.disease-group-link{align-items:center;color:grey;display:inline-flex;font-size:12px;gap:5px;line-height:1.5;text-decoration:none}.disease-group-link-icon{flex:none;height:12px;opacity:.75;width:12px}.disease-group-link:focus-visible .disease-group-link-icon,.disease-group-link:hover .disease-group-link-icon{opacity:1}.material-symbols-outlined.disease-group-link-out{font-size:13px;margin-bottom:0;opacity:.7}.disease-group-link:focus-visible .disease-group-link-out,.disease-group-link:hover .disease-group-link-out{opacity:1}.disease-group-link>span:not(.disease-group-link-out){border-bottom:1px solid #0000}.visually-hidden{clip:rect(0 0 0 0);border:0;height:1px;margin:-1px;overflow:hidden;padding:0;position:absolute;white-space:nowrap;width:1px}.disease-group-link:focus-visible,.disease-group-link:hover{color:#5a5a5a}.disease-group-link:focus-visible>span:not(.disease-group-link-out),.disease-group-link:hover>span:not(.disease-group-link-out){border-bottom-color:initial}body.dark-mode .disease-group-link{color:#8f8f8f}body.dark-mode .disease-group-link:focus-visible,body.dark-mode .disease-group-link:hover{color:silver}.soon-badge{background:#0d6efd;border-radius:10px;color:#fff;display:inline-block;font-size:10px;font-weight:500;line-height:1.3;max-width:100%;padding:3.5px 10px;position:relative;text-align:center;top:3px}body.dark-mode .soon-badge{background:#1a5bdb;color:#fff}:root{--color-bg:#f7f9fc;--color-card:#fff;--color-text:#0f172a;--color-muted:#64748b;--color-border:#e2e8f0;--color-primary:#2563eb;--color-primary-hover:#1d4ed8;--color-danger:#dc2626;--shadow:0 8px 24px #02081714}body.dark-mode{--color-bg:#0b1220;--color-card:#0f172a;--color-text:#e5e7eb;--color-muted:#94a3b8;--color-border:#1f2937;--color-primary:#38bdf8;--color-primary-hover:#0ea5e9;--color-danger:#f87171;--shadow:0 10px 30px #00000073}.signup-container{margin:32px auto;max-width:760px;padding:0 16px}.form-card{background:#fff;background:var(--color-card);border:1px solid #e2e8f0;border:1px solid var(--color-border);border-radius:12px;box-shadow:0 8px 24px #02081714;box-shadow:var(--shadow);color:#0f172a;color:var(--color-text);padding:24px}.form-title{font-size:24px;font-weight:700;letter-spacing:.2px;line-height:1.2;margin:0 0 4px}.form-subtitle{color:#64748b;color:var(--color-muted);font-size:14px;margin:21px 0 30px}.form-divider{background:#e2e8f0;background:var(--color-border);border:0;height:1px;margin:8px 0 16px}.signup-form{margin-top:8px}.form-group{margin-bottom:16px}.form-row{display:flex;flex-wrap:wrap;gap:1rem}.form-group.half{flex:1 1;min-width:200px}.form-label{display:block;font-weight:600;margin-bottom:6px}.required-asterisk{color:#dc2626;color:var(--color-danger);margin-left:4px}.form-input,.form-textarea{background:#0000;border:1px solid #e2e8f0;border:1px solid var(--color-border);border-radius:8px;box-sizing:border-box;color:#0f172a;color:var(--color-text);font-size:14px;padding:10px 12px;transition:border-color .12s ease,box-shadow .12s ease;width:100%}.form-input::placeholder,.form-textarea::placeholder{color:#64748b;color:var(--color-muted)}.form-input:focus,.form-textarea:focus{border-color:#2563eb;border-color:var(--color-primary);box-shadow:0 0 0 3px color-mix(in srgb,#2563eb 20%,#0000);box-shadow:0 0 0 3px color-mix(in srgb,var(--color-primary) 20%,#0000);outline:none}.form-textarea{min-height:96px;resize:vertical}.help-text{color:#64748b;color:var(--color-muted);font-size:12px;margin-top:6px}.gdpr-box{background:color-mix(in srgb,#e2e8f0 18%,#0000);background:color-mix(in srgb,var(--color-border) 18%,#0000);border:1px solid #e2e8f0;border:1px solid var(--color-border);border-radius:8px;font-size:13px;line-height:1.45;overflow-y:auto;padding:10px 12px}.gdpr-box p{margin:0 0 8px}.gdpr-box p:last-child{margin-bottom:0}.checkbox-row{align-items:flex-start;color:#0f172a;color:var(--color-text);display:flex;font-size:13px;gap:8px;margin-top:10px}.checkbox-row input[type=checkbox]{margin-top:2px}.alert{border:1px solid #e2e8f0;border:1px solid var(--color-border);border-left-width:4px;border-radius:8px;margin-bottom:16px;padding:12px 14px}.alert:focus{outline:2px solid color-mix(in srgb,#2563eb 45%,#0000);outline:2px solid color-mix(in srgb,var(--color-primary) 45%,#0000);outline-offset:2px}.alert-title{display:block;margin-bottom:4px}.alert-error{background:color-mix(in srgb,#dc2626 10%,#0000);background:color-mix(in srgb,var(--color-danger) 10%,#0000);border-left-color:#dc2626;border-left-color:var(--color-danger)}.alert-error,.alert-warning{color:#0f172a;color:var(--color-text)}.alert-warning{background:color-mix(in srgb,#f59e0b 12%,#0000);border-left-color:#d97706}.alert-success{background:color-mix(in srgb,#10b981 12%,#0000);border-left-color:#059669;color:#0f172a;color:var(--color-text)}.form-actions{display:flex;gap:12px;margin-top:20px}.btn{align-items:center;border:1px solid #0000;border-radius:10px;cursor:pointer;display:inline-flex;font-size:14px;font-weight:600;gap:8px;justify-content:center;padding:10px 16px;transition:transform 80ms ease,background-color .12s ease,box-shadow .12s ease}.btn:disabled{cursor:not-allowed;opacity:.6}.btn-primary{background:#2563eb;background:var(--color-primary);box-shadow:0 6px 14px color-mix(in srgb,#2563eb 28%,#0000);box-shadow:0 6px 14px color-mix(in srgb,var(--color-primary) 28%,#0000);color:#fff}.btn-primary:hover:not(:disabled){background:#1d4ed8;background:var(--color-primary-hover);transform:translateY(-1px)}.form-alt{color:#64748b;color:var(--color-muted);font-size:14px;margin:12px 0 0}.form-alt .link,.link{color:#2563eb;color:var(--color-primary);text-decoration:none}.form-alt .link:hover,.link:hover{text-decoration:underline}.alert-success-spacing{margin-top:28px}.verify-page{background:radial-gradient(1200px 650px at 10% -10%,#0e749029,#0000 60%),radial-gradient(900px 500px at 90% 110%,#2563eb24,#0000 55%),linear-gradient(180deg,#f8fafc,#eef2ff);color:#0f172a;display:grid;min-height:100vh;padding:24px;place-items:center}.verify-card{background:#fff;border:1px solid #cbd5e1;border-radius:16px;box-shadow:0 22px 40px #02061721;max-width:620px;padding:28px;width:100%}.verify-eyebrow{color:#0369a1;font-size:12px;font-weight:700;letter-spacing:.08em;margin:0;text-transform:uppercase}.verify-title{color:#0f172a;font-size:30px;line-height:1.12;margin:8px 0 6px}.verify-subtitle{color:#334155;font-size:15px;margin:0 0 18px}.verify-status{background:#f8fafc;border:1px solid #cbd5e1;border-radius:12px;color:#0f172a;font-size:15px;line-height:1.5;padding:14px 16px}.verify-status-loading{background:#f0f9ff;border-color:#bae6fd}.verify-status-already,.verify-status-success{background:#dcfce7;border-color:#22c55e;color:#166534}.verify-status-error{background:#fef2f2;border-color:#fecaca;color:#991b1b}.verify-actions{margin-top:16px}.verify-btn{align-items:center;border-radius:10px;display:inline-flex;font-size:14px;font-weight:600;justify-content:center;padding:10px 16px;text-decoration:none;transition:transform 80ms ease,box-shadow .12s ease,background-color .12s ease}.verify-btn-primary{background:#0f172a;box-shadow:0 8px 16px #0f172a38;color:#fff}.verify-btn-primary:hover{background:#020617;transform:translateY(-1px)}.verify-btn-secondary{background:#fff;border:1px solid #94a3b8;color:#0f172a}.verify-btn-secondary:hover{background:#f8fafc}@media (max-width:640px){.verify-page{padding:14px}.verify-card{padding:20px}.verify-title{font-size:24px}}
/*# sourceMappingURL=main.787da570.css.map*/